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Wilmington, Delaware U.S.A. 19901
Tel: 1-302-123-7777
Axon-II pf-NCS White Paper Research
Peer Review Studies and Scientific Presentations
PUBLISHED PEER-REVIEWED STUDY
Predicting Nerve Root Pathology With Voltage-actuated Sensory Nerve Conduction Threshold
A 3 year class I study on failed back and chronic A-delta measurements shows 95% sensitivity in detecting nerve-root pathology.
AASEM MULTICENTER STUDY
Paradoxical Relationship: A-Delta Function and VAS
Abstract: The A-delta pain fiber nerve conduction study (A-delta pf-NCS) measures the sensitivity of fast pain fibers known to down-regulate soon after injury. This study compares changes in the sensitivity of the A-delta fibers in pathological nerve-roots with changes in the patient's subjective visual analog score (VAS). A significantly close relationship was found between the change in voltage required to cause an action potential (nerve impulse) in the A-delta fibers of the pathological nerve-root and changes in the subjective VAS rating. The findings support the utility of the A-delta pf-NCS for detecting the level and side of painful radiculopathy and measuring changes in pain.
PUBLISHED PEER-REVIEWED STUDY
A-Delta Analysis Helps Identify Piriformis Syndrome
Summary: This retrospective study of 50 patients found an 80% probability of concomitant piriformis entrapment syndrome when the A-delta NCS detected abnormality at L5 and S1 on the ipsilateral side.
PRESENTED: SCIENTIFIC MEETING - 2002 - AMERICAN SOCIETY OF REGIONAL ANAESTHESIOLOGY (A.S.R.A.) & PAIN MEDICINE
A-Delta EDX Gets to the (Nerve) Root of Fibromyalgia
Summary: Using the A-delta NCS, LSU Pain Center found the majority of fibromyalgia patients to have previously undiagnosed nerve-root pathology. Ten treated patients were available for a six month to one-year follow-up and all ten were found to be free of fibromyalgia symptoms.
PRESENTED: AMERICAN COLLEGE OF SURGEONS - OCT. 10, 2008
Chronic Prostatitis Causing Pelvic Pain Due To Sacral Entrapment
Pain fiber NCS reveals lumbosacral nerve root lesions associated with prosatitis and pelvic pain syndromes. American College of Surgeons. October 10, 2008.
PRESENTED: SCIENTIFIC MEETING - 2008 - AMERICAN ACEDEMY OF PAIN MEDICINE
A-Delta Fiber EDX Shows Correlation to VAS Scores
Alex Ambroz, MD Associate Clinical Professor John Marshall University Medical School
PRESENTED: SCIENTIFIC MEETING - 2007- A.A.S.E.M. ANNUAL CONFERENCE
A-Delta Pathology Correlation to Abnormal Vertebral Motion
Nerve root injury detected by A-delta NCS correlates with abnormal motion (reversed coupled motion) of the vertebral segment above and/or below the injured nerve root.
PRESENTED: SCIENTIFIC MEETING - 2007 - A.A.S.E.M. ANNUAL CONFERENCE
A-Delta Analysis
Presentation explains the interpretation of A-delta data using a nomogram. Shows how the patient acts as his own control allowing accuracy approaching 100%, as compared to comparison with population averages with 67% accuracy.
PRESENTED: SCIENTIFIC MEETING - 2008 - A.A.S.E.M. ANNUAL CONFERENCE
Using A-Delta NCS to Target Transforaminal Blocks
A-delta NCS helps to diagnose severity, location and distribution of radiculopathy. Abnormally high A-delta NCS measures indicate significant nerve conduction loss. Abnormally low A-delta NCS measures indicate hyper-esthetic state corresponding with inflamed, irritated or regenerating nerves.
STUDY CORRELATION WITH RADICULOPATHY AND FIBROMYALGIA
Online: European Spine Journal - Study Support Fibromyalgia is Spine Related
Study supports a correlation between cervical radiculopathy and fibromyalgia. Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications. Some patients with fibromyalgia also exhibit the neurological signs of cervical myelopathy. We sought to determine if treatment of cervical myelopathy in patients with fibromyalgia improves the symptoms of fibromyalgia and the patients' quality of life.
STUDY SUPPORT A-DELTA STIMULATION DEPRESSES SYNAPTIC FUNCTION
The Journal of Neuroscience - Supports A-Delta Stimulation Depresses Synapses
Title: Low-Frequency Stimulation of Afferent A-delta Fibers Induces Long-Term Depression at Primary Afferent Synapses with Substantia Gelatinosa Neurons in Rats.
STUDY SUPPORTS A-DELTA RESPOND TO HIGHER FREQUENCY THAN C-TYPE FIBERS
Online: A.P.S. Journal of Physiology
Title: Response Properties of Thin Myelinated A-delta Fibers in Human Skin Nerves
Study supports that A-delta fibers respond to higher frequency stimulation than C-Type fibers.
PUBLISHED PEER-REVIEWED STUDY
Predicting Nerve Root Pathology With Voltage-actuated Sensory Nerve Conduction Threshold
A 3 year class I study on failed back and chronic A-delta measurements shows 95% sensitivity in detecting nerve-root pathology.
AASEM MULTICENTER STUDY
Paradoxical Relationship: A-Delta Function and VAS
Abstract: The A-delta pain fiber nerve conduction study (A-delta pf-NCS) measures the sensitivity of fast pain fibers known to down-regulate soon after injury. This study compares changes in the sensitivity of the A-delta fibers in pathological nerve-roots with changes in the patient's subjective visual analog score (VAS). A significantly close relationship was found between the change in voltage required to cause an action potential (nerve impulse) in the A-delta fibers of the pathological nerve-root and changes in the subjective VAS rating. The findings support the utility of the A-delta pf-NCS for detecting the level and side of painful radiculopathy and measuring changes in pain.
PUBLISHED PEER-REVIEWED STUDY
A-Delta Analysis Helps Identify Piriformis Syndrome
Summary: This retrospective study of 50 patients found an 80% probability of concomitant piriformis entrapment syndrome when the A-delta NCS detected abnormality at L5 and S1 on the ipsilateral side.
PRESENTED: SCIENTIFIC MEETING - 2002 - AMERICAN SOCIETY OF REGIONAL ANAESTHESIOLOGY (A.S.R.A.) & PAIN MEDICINE
A-Delta EDX Gets to the (Nerve) Root of Fibromyalgia
Summary: Using the A-delta NCS, LSU Pain Center found the majority of fibromyalgia patients to have previously undiagnosed nerve-root pathology. Ten treated patients were available for a six month to one-year follow-up and all ten were found to be free of fibromyalgia symptoms.
PRESENTED: AMERICAN COLLEGE OF SURGEONS - OCT. 10, 2008
Chronic Prostatitis Causing Pelvic Pain Due To Sacral Entrapment
Pain fiber NCS reveals lumbosacral nerve root lesions associated with prosatitis and pelvic pain syndromes. American College of Surgeons. October 10, 2008.
PRESENTED: SCIENTIFIC MEETING - 2008 - AMERICAN ACEDEMY OF PAIN MEDICINE
A-Delta Fiber EDX Shows Correlation to VAS Scores
Alex Ambroz, MD Associate Clinical Professor John Marshall University Medical School
PRESENTED: SCIENTIFIC MEETING - 2007- A.A.S.E.M. ANNUAL CONFERENCE
A-Delta Pathology Correlation to Abnormal Vertebral Motion
Nerve root injury detected by A-delta NCS correlates with abnormal motion (reversed coupled motion) of the vertebral segment above and/or below the injured nerve root.
PRESENTED: SCIENTIFIC MEETING - 2007 - A.A.S.E.M. ANNUAL CONFERENCE
A-Delta Analysis
Presentation explains the interpretation of A-delta data using a nomogram. Shows how the patient acts as his own control allowing accuracy approaching 100%, as compared to comparison with population averages with 67% accuracy.
PRESENTED: SCIENTIFIC MEETING - 2008 - A.A.S.E.M. ANNUAL CONFERENCE
Using A-Delta NCS to Target Transforaminal Blocks
A-delta NCS helps to diagnose severity, location and distribution of radiculopathy. Abnormally high A-delta NCS measures indicate significant nerve conduction loss. Abnormally low A-delta NCS measures indicate hyper-esthetic state corresponding with inflamed, irritated or regenerating nerves.
STUDY CORRELATION WITH RADICULOPATHY AND FIBROMYALGIA
Online: European Spine Journal - Study Support Fibromyalgia is Spine Related
Study supports a correlation between cervical radiculopathy and fibromyalgia. Treatment of cervical myelopathy in patients with the fibromyalgia syndrome: outcomes and implications. Some patients with fibromyalgia also exhibit the neurological signs of cervical myelopathy. We sought to determine if treatment of cervical myelopathy in patients with fibromyalgia improves the symptoms of fibromyalgia and the patients' quality of life.
STUDY SUPPORT A-DELTA STIMULATION DEPRESSES SYNAPTIC FUNCTION
The Journal of Neuroscience - Supports A-Delta Stimulation Depresses Synapses
Title: Low-Frequency Stimulation of Afferent A-delta Fibers Induces Long-Term Depression at Primary Afferent Synapses with Substantia Gelatinosa Neurons in Rats.
STUDY SUPPORTS A-DELTA RESPOND TO HIGHER FREQUENCY THAN C-TYPE FIBERS
Online: A.P.S. Journal of Physiology
Title: Response Properties of Thin Myelinated A-delta Fibers in Human Skin Nerves
Study supports that A-delta fibers respond to higher frequency stimulation than C-Type fibers.